McGettigan, Patricia

Patricia McGettigan

Reader in Clinical Pharmacology and Medical Education (HCC)

Patricia McGettigan trained in pharmacy and then in medicine at the University of Dublin, Trinity College. She joined the Department of Clinical Pharmacology at the University of Newcastle, New South Wales, Australia in 1997, developing skills in pharmacoeconomics and medicines evaluation, undertaking epidemiological studies of cardiovascular side effects associated with non-steroidal anti-inflammatory drugs (NSAIDs), working as clinician in general medicine and clinical toxicology, and leading the medicine component of the final year undergraduate medical curriculum at the University of Newcastle. Moving to Hull York Medical School in 2007, she co-developed the final year curriculum, set up and led the interprofessional training ward, prescribing teaching program, and whole class clinical teaching program.  She joined Professor Mark Caulfield’s group at WHRI in October 2011 undertaking responsibility for clinical pharmacology and therapeutics teaching in the undergraduate medical curriculum, contributing to patient care in the cardiology unit at The London Hospital and establishing with colleagues in HIV medicine a specialist HIV-cardiovascular risk management clinic. Her current research is pharmacoepidemiology-focused and includes collaborations on medicines access studies with the QMUL Global Health, Policy and Innovation Unit, investigations on the mitigation of NSAID-associated adverse events with colleagues in the Department of Cardiology at the University of Copenhagen and examination of co-morbidities among HIV-positive people in the UK with Barts Health Trust and the Farr Institute.

Summary of Research

Patricia McGettigan’s research has two primary strands, pharmacoepidemiology and medical education. In pharmacoepidemiology, her work focuses on non-steroidal anti-inflammatory drugs (NSAIDs) and includes primary research in the form of case control studies of cardiac side effects of NSAID use and investigation of genetic susceptibilities for NSAID-associated cardiovascular events as well as meta-analyses of studies of NSAID-associated gastro-intestinal and cardiovascular events. In medical education, her research includes evaluation of the impact of undergraduate interprofessional training on the subsequent performance of new doctors, the development of methods to evaluate multi-disciplinary team-working skills in hospital settings, and evaluation of multi-modal prescribing training for final year medical students. 

 

Key Publications

For a full list of publist publications click here

McGettigan P, Roderick P, Mahajan R, Kadam A, Pollock AM (2015) Use of Fixed Dose Combination (FDC) drugs in India: Central regulatory approval and sales of FDCs containing non-steroidal anti-inflammatory drugs (NSAIDs), metformin, or psychotropic drugs. In Press. PLoS Medicine; Accepted 3 April 2015

Schjerning Olsen, AM., Gislason, G.H., McGettigan, P., Fosbøl, E., Sørensen, R., Lock Hansen, M., Køber, L., Torp-Pedersen, C., Lamberts, M. (2015) Association of NSAID use with risk of bleeding and cardiovascular events in patients receiving antithrombotic therapy after myocardial infarction JAMA, 313(8):805-814. doi:10.1001/jama.2015.0809  

 Roderick, P., Mahajan, R., McGettigan, P., Pollock, A. (2014). India should introduce a new Drugs Act. Lancet, Vol.383, (9913) 203-206. http://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736%2814%2960059-3.pdf

Roderick, P., Mahajan, R., McGettigan, P., Pollock, A., Jeffery, R. (2014). Need for a new Drugs Bill. Economic & Political Weekly, XLIX(33):15-19.

 McGettigan, P., & Henry, D. (2013) Use of non-steroidal anti-inflammatory drugs that elevate cardiovascular risk: an examination of sales and essential medicines lists in low-, middle-, and high-income countries. PLoS Med, 10(2), e1001388. doi: 10.1371/journal.pmed.1001388

 McGettigan, P., McKendree, J., Reed, N., Holborow, S., Walsh, C. D., & Mace, T. (2013) Identifying attributes required by Foundation Year 1 doctors in multidisciplinary teams: a tool for performance evaluation. BMJ Qual Saf, 22(3), 225-232. doi:10.1136/bmjqs-2012-001418

 McGettigan, P., & Henry, D. (2011) Cardiovascular risk with non-steroidal anti-inflammatory drugs: systematic review of population-based controlled observational studies. PLoS Med, 8(9), e1001098. doi:10.1371/journal.pmed.1001098

 

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