Pugliese, Francesca

Francesca Pugliese

Reader in Radiology (HCC) / Consultant in Advanced Cardiovascular Imaging

I qualified from Medical School of University of Genoa in 2000. My clinical training in imaging took place in Genoa. I was awarded my certificate of completion of  specialty training in 2004. I then joined the non-invasive cardiac imaging group at the Thoraxcentre/Erasmus MC University Medical Centre Rotterdam (the  Netherlands) and received my PhD with honors in 2008 entitled “Computed tomography of the coronary arteries”. Supported by a grant from the European  Society of Cardiology, I moved to the UK in 2008. Since then I have worked for the Royal Brompton hospital and in the Cardiology group of the Medical Research  Council (MRC) Clinical Sciences Centre, Imperial College London, at Hammersmith Hospital, in cardiovascular hybrid imaging (PET/CT). After contributing to the  clinical service of the Essex Cardiothoracic Centre in Essex in 2009, I joined the Centre for Advanced Cardiovascular Imaging and the NIHR Cardiovascular  Biomedical Research Unit at Barts as a Senior Clinical Lecturer in May 2010.  My main clinical and research interests are technical and clinical aspects related to  non-invasive cardiac imaging (cardiac computed tomography, cardiac magnetic resonance, nuclear cardiology) in a range of heart conditions. I am a member of  the Nucleus of the Working Group in Nuclear Cardiology and Cardiac CT of the ESC, an executive committee member of the British Society of Cardiovascular  Imaging and a Specialist Committee Member for NICE Diagnostic Assessment Programme.

Summary of Research

My research interests are directed towards the development, technical optimization and clinical implementation of multimodal non-invasive imaging, including  computed tomography, positron emission tomography/hybrid imaging and magnetic resonance imaging in a range of heart conditions with focus on ischaemic  heart disease.

Key Publications

For a full list of publist publications click here

Genders T, Steyerberg E, Alkhadi H, Pugliese F, Petersen SE, Davies LC, Hunink MGM (CAD Consortium). A Prediction Model for the Presence of Coronary Artery Disease: a pooled analysis of existing cohorts. The British Medical Journal (BMJ) 2012; 344:e3485.

Genders TS, Steyerberg, EW, Alkadhi H, Pugliese F, Hunink MG (CAD Consortium). A clinical prediction rule for the diagnosis of coronary artery disease: validation, updating, and extension. Eur Heart J 2011; 32(11):1316-1330. doi:10.1093/eurheartj/ehr014

Lamare F, Hinz R, Gaemperli O, Pugliese F, Mason JC, Spinks T, Camici PG, Rimoldi OE. Detection and quantification of large-vessel inflammation with 11C-(R)-PK11195 PET/CT. J Nucl Med 2011; 52(1):33-39. doi:10.2967/jnumed.110.079038

Pugliese F, Gaemperli O, Kinderlerer AR, Lamare F, Shalhoub J, Davies AH, Rimoldi OE, Mason JC, Camici PG. Imaging of Vascular Inflammation with [11C]-PK11195 and PET/CT Angiography. J Am Coll Cardiol 2010; 56(8):653- 661.

Ferrante G, Pugliese F, Di Mario C. Jugular venous pressure: a cardinal sign. The Lancet 2010; 376(9743):802-802. doi:10.1016/S0140-6736(09)61502-6

Pugliese F. Gadolinium-enhanced coronary CT angiography: improved safety? Heart 2010; 96(19):1513-1515. doi:10.1136/hrt.2010.195180

Pugliese F, Hunink MGM, Gruszczynska K, Alberghina F, Malago’ R, van Pelt N, Mollet NR, Cademartiri F, Weustink A, Meijboom WB, Witteman C, de Feyter PJ, Krestin GP. Multislice Computed Tomography Coronary Angiography: Effect of Experience and Training on Reader Performance. Radiology 2009; 251(2):359-368. doi:10.1148/radiol.2512080384

Ramcharitar S, Pugliese F, Schultz C, Ligthart J, de Feyter P, Li H, Mollet N., van de Ent, M, Serruys, PW, van Geuns, RJ. Integration of Multislice Computed Tomography With Magnetic Navigation Facilitates Percutaneous Coronary Interventions Without Additional Contrast Agents. J Am Coll Cardiol 2009; 53(9):741-746. doi:10.1016/j.jacc.2008.10.050

Weustink AC, Nieman K, Pugliese F, Mollet NR, Meijboom BW, van Mieghem C, ten Kate GJ, Cademartiri F, Krestin GP, de Feyter PJ. Diagnostic Accuracy of Computed Tomography Angiography in Patients After Bypass Grafting Comparison With Invasive Coronary Angiography. JACC Cardiovasc Imaging 2009; 2(7):816-824. doi:10.1016/j.jcmg.2009.02.010

Pugliese F, Mollet NR, Hunink MG, van Domburg R, Nieman K, van Mieghem C, de Feyter PJ, Krestin GP. Diagnostic accuracy of coronary CT angiography with different generation scanners. Single-centre experience. Radiology 2008; 246(2):384-393. doi:10.1148/radio1.2462070113

Pugliese F, Weustink AC, Van Mieghem C, Alberghina F, Otsuka M, Meijboom WB, Van Pelt N, Mollet NR, Cademartiri F, Krestin GP, Hunink MGM, de Feyter PJ. Dual-source coronary computed tomography angiography for detecting instent restenosis. Heart 2008; 94(7):848-854. doi:10.1136/hrt.2007.126474 

Pugliese F, Mollet NR, Runza G, van Mieghem C, Meijboom WB, Malagutti P, Baks T, Krestin GP, deFeyter PJ, Cademartiri F. Diagnostic accuracy of non-invasive 64-slice CT coronary angiography in patients with stable angina pectoris. Eur Radiol 2006; 16(3):575-582. doi:10.1007/s00330-005-0041-0

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